Endocrine Abstracts

Introduction: Diabetes is a disease that can slowly be. Among its complications, erectile dysfunction can appear. Be careful, these problems can be warning signs. These problems can be warning signs, especially cardiovascular, but they also have significant psychological retention.Materials and methods: Prospective study on 37 diabetic patients collegiate in the department of Endocrinology CHU Hedi Chaker Sfax Tunisia. All patients are assessed for erect...

Background/Aim: Since diabetes is the most common endocrine disorder and the diabetic ketoacidosis (DKA) is considered as a medical emergency, our aim was to determinate the frequency of symptoms and precipitating factors of DKA in type 1 and type 2 diabetesMethods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between August 2021 to December 2022. We compared the di...

Introduction: Anemia is defined by the World Health Organization as a hemoglobin concentration less than 120 g/l in women outside of pregnancy, and less than 130 g/l in men over 15 years of age. It is common in diabetics. It can be due to an autoimmune disease associated with type 1 diabetes, whereas the inflammatory cause is the primary cause in type 2 diabetes.Observation: This is a 75 year old patient, type 2 diabetic for 21 years on insulin analogues...

The autoimmune thyroid disease (AITDs) comprises two clinical phenotype, Graves’ disease (GD) and autoimmune hypothyroidism (AIH), which include goitrous [Hashimoto thyroiditis (HT)] and non goitrous forms [Primary idiopathic myxoedema (PIM)]. These disorders are characterized by loss of immunological self tolerance including the presence of a thyroid lymphocytic infiltrate and autoantibodies to thyroglobulin (Tg) and thyroid peroxidase (TPO). Inheritance of AITDs is comp...

Introduction: The metabolic stressor, hypoglycemia, elicits integrated counterregulatory responses, including activation of the hypothalamic–pituitary–adrenal axis. However, it is suggested that recurring insulin-induced hypoglycemia can impair this counter-regulation. Here we report three cases of patients with isulinoma and corticotroph deficiency.Case reports: The first case, 38-year-old man was referred because of recurrent episode...

Introduction: Disorders of sex development (DSD) is a congenital condition in which the development of chromosomal, gonadal or genital sex is atypical. A female appearance patient with secondary amenorrhea and 46 XY karyotype seems to be solid evidences to diagnose Y-chromosome-related DSD diseases, while it is not necessarily the accurate diagnosis. We here report a case of a 16- year-old girl with secondary amenorrhea and 46 XY karyotype after bone marrow transplantation (BM...

Introduction: Diabetic foot infection (DFI) is a major public health problem, both for its morbid clinical consequences mainly ulcers and the economic social cost due to repeated hospitalisations and the high rate of amputation.Objectives: Analyse the clinical presentation of DFI, study risk factors of developing this infection and describe the therapeutic management.Materials and methods: Retrospective study spread over 8 years ol...

Introduction: Primary amyloidosis is a multi-systemic disease difficult to identify given the diversity of the disorders that it can cause especially at an early stage of the disease. This makes its diagnosis difficult in case of association with a pathology that can be intricate with its clinical expression. In this context we report the first case in the literature associating mitochondrial diabetes (DM) with a primary amyloidosisCase: A 32 years old g...

IntroductionThe association of type 1 diabetes with other autoimmune diseases is well known due to a common genetic terrain of varied clinical expressions. However, the occurrence of systemic diseases in diabetic patient, whatever the type of diabetes, is poorly studied. The objective of this study is to describe autoimmune and inflammatory diseases associated with diabetes.Materials and methodsIt ’ s a ...

IntroductionNon-functioning pituitary adenomas (NFPA) present approximately 15% to 30% of all pituitary adenomas. They are most commonly misdiagnosed, until they are large enough to lead to mass effect and hypopituitrasm. The present study was carried out with the aim of studying the clinical and biological characteristics of patients who are followed for NFA.Patients and methodsThis is a retrospective study ...